Model
Digital Document
Publisher
Florida Atlantic University
Description
Compositions and methods for reducing neovascularization.
Purified nucleic acid constructs and vectors encoding an antiangiogenic
protein operably linked to a GFAP promoter. Vectors
can include at least one hypoxia regulated element,
enhancer element and silencer element. Gene therapy methods
for reducing, delaying or preventing neovascularization
based on the nucleic acid constructs and vectors.
Purified nucleic acid constructs and vectors encoding an antiangiogenic
protein operably linked to a GFAP promoter. Vectors
can include at least one hypoxia regulated element,
enhancer element and silencer element. Gene therapy methods
for reducing, delaying or preventing neovascularization
based on the nucleic acid constructs and vectors.
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