Mutlu, Caner

Every passenger vehicle must rely on a safe and optimal trajectory to eliminate traffic incidents and congestion as well as to reduce environmental impact, and travel time. Autonomous intersection management systems (AIMS) enable large scale optimization of vehicular trajectories with connected and autonomous vehicles (CAVs). The first contribution of this dissertation is the fastest trajectory planner (FTP) method which is geared for computing the fastest waypoint trajectories via performing graph search over a discretized space-time (ST) graph (Gt), thereby constructing collision-free space-time trajectories with variable vehicular speeds adhering to traffic rules and dynamical constraints of vehicles. The benefits of navigating a connected and autonomous vehicle (CAV) truly capture effective collaboration between every CAV during the trajectory planning step. This requires addressing trajectory planning activity along with vehicular networking in the design phase. For complementing the proposed FTP method in decentralized scenarios, the second contribution of this dissertation is an application layer V2V solution using a coordinator-based distributed trajectory planning method which elects a single leader CAV among all the collaborating CAVs without requiring a centralized infrastructure. The leader vehicular agent calculates and assigns a trajectory for each node CAV over the vehicular network for the collision-free management of an unsignalized road intersection. The proposed FTP method is tested in a simulated road intersection scenario for carrying out trials on scheduling efficiency and algorithm runtime. The resulting trajectories allow high levels of intersection sharing, high evacuation rate, with a low algorithm single-threaded runtime figures even with large scenarios of up to 1200 vehicles, surpassing comparable systems.

A cerebrospinal fluid (CSF) shunt system is used for treatment of hydrocephalus and abnormal intracranial pressure (ICP) conditions. Mostly a shunt system is placed under skin for creating a low resistance pathway between intracranial space and appropriate discharge sites within body by doing so excess CSF volume can exit the intracranial space. Displaced intracranial CSF volume normally results in lowered ICP. Thereby, a CSF shunt can manage ICP. In a healthy person, normal ICP is primarily maintained by CSF production and reabsorption rate as a natural tendency of body. If intracranial CSF volume starts increasing due to under reabsorption, this mostly results in raised ICP. Abnormal ICP can be treated by discharging excess CSF volume via use of a shunt system. Once a shunt system is placed subcutaneously, a patient is expected to live a normal life. However, shunt failure as well as flow regulatory problems are major issues with current passive shunt systems which leaves patients with serious consequences of under-/over CSF drainage condition. In this research, a shunt system is developed which is resistant to most shunt-related causes of under-/over CSF drainage. This has been made possible via use of an on-board medical monitoring (diagnostic) and active flow control mechanism. The developed shunt system, in this research, has full external ventricular drainage (EVD) capability. Further miniaturization will make it possible for an implantable shunt.